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/Title (Neural network models of protein domain evolution)
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/Subject (Protein domains are complex adaptive systems, and here a novel procedure is presented that models the evolution of new functional sites within stable domain folds using neural networks. Neural networks, which were originally developed in cognitive science for the modeling of brain functions, can provide a fruitful methodology for the study of complex systems in general. Ethical implications of developing complex systems models of biomolecules are discussed, with particular reference to molecular medicine.)
/Keywords (models in biochemistry; protein domain evolution; neural networks; ethics of modeling)
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Neural network models of protein domain evolution
Sylvia Nagl
Protein domains are complex adaptive systems, and here a novel procedure is presented that models the evolution of new functional sites within stable domain folds using neural networks. Neural networks, which were originally developed in cognitive science for the modeling of brain functions, can provide a fruitful methodology for the study of complex systems in general. Ethical implications of developing complex systems models of biomolecules are discussed, with particular reference to molecular medicine.
models in biochemistry
protein domain evolution
neural networks
ethics of modeling
Copyright 2000 by HYLE and Sylvia Nagl
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http://www.hyle.org
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